Achievement

.原著論文

　　*, corresponding author.

  • 1. Mori, A., Shiroishi, T., Fujioka, J., Nakajima, T., Mitsui, S., Suginoma, H., Kakuta Y., Zen, H., *Nakamura, K., Infrared free electron laser-irradiated polyleucine does not exert aggregates-induced aversive effects on mouse brain. Brain Dioroders 14, 100137. https://doi.org/10.1016/j.dscb.2024.100137
    2. Kitazawa, K., Tsuchiya, K., Hirao, K., Furukawa, T., Tozato, F., Iwaya, T., *Mitsui, S. Escalation of Kihon Checklist Scores Preceding Long-Term Care Certification: A 9-Year Retrospective Study. Health Services Research & Managerial Epidemiology 11, 23333928241247027. https://doi.org/10.1177/23333928241247027
    3. Miyata, S., Tsuda, M., *Mitsui, S. Overexpression of motopsin, an extracellular serine protease related to intellectual disability, promotes adult neurogenesis and neuronal responsiveness in the dentate gyrus. Molecular Neurobiology, in press. https://doi.org/10.1007/s12035-023-03890-y
    4. Takeuchi, Y., Yamashiro, K., Noguchi, A., Liu, J., Mitsui, S., Ikegaya, Y., *Matsumoto, N. Machine learning-based sgmentation of the rodent hippocampal CA2 area from Nissl-stained sections. Frontiers in Neuroanatomy 17, 1172512, 2023. https://doi.org/10.3389/fnana.2023.1172512
    5. *Hidaka, C., Mitsui, S., Osako, Y., Takahashi, K., Tanaka, K., Yuri, K. Differential brain expression pattern of Sez6 alternative splicing isoform with deleted transmembrane domain. Biochemical and Biophysical Research Communication 636, 128–132, 2022. https://doi.org/10.1016/j.bbrc.2022.10.103
    6. Owada, R., Kakuta, Y., Yoshida, K., Mitsui, S., *Nakamura, K. Conditioned medium from BV2 microglial cells having polyleucine specifically alters startle response in mice. Scientific Reports 12, 18718, 2022. https://doi.org/10.1038/s41598-022-23571-5
    7. *Tsuchiya, K., Shimoda, K., Mitsui, S., Yamaya, N., Kikuchi, S., Fujita, T, Tozato, F. Hemodynamic changes in the right ventrolateral prefrontal cortex relate to the psychological mood profile. Neuroscience Letters 780, 136653, 2022. https://doi.org/10.1016/j.neulet.2022.136653
    8. Owada, T., Mitsui, S., *Nakamura, K. Exogenous polyserine and polyleucine are toxic to recipient cells. Scientific Reports 12, 1685, 2022. https://doi.org/10.1038/s41598-022-05720-y
    9. *Okuda, T., Osako, Y., Hidaka, C., Nishihara, M., Young, L. J., Mitsui, S., Yuri, K., Separation from a bonded partner alters neural response to inflammatory pain in monogamous rodents. Behavioural Brain Research 418, 113650, 2022. https://doi.org/10.1016/j.bbr.2021.113650
    10. Hirota, Y., Otsuki, C., Kamura, E., *Mitsui, S., Intracerebral delivery of an OTR antagonist and subsequent behavioral testing in prairie voles. Methods in Molecular Biology 2384, 257–269, 2022. https://doi.org/10.1007/978-1-0716-1759-5_16
    11. Miyata, S., Kashio, T., Tsuchiya, K., *Mitsui, S., Motopsin deficiency imparts partial insensitivity to doxorubicin-induced hippocampal impairments in adult mice. Neuroscience Letters 763, 136181, 2021. https://doi.org/10.1016/j.neulet.2021.136181
    12. Hirota, Y., Arai, A., Young, L. J., Osako, Y., Yuri, K., *Mitsui, S., Oxytocin receptor antagonist reverses the blunting effect of pair bonding on fear learning in monogamous prairie voles. Hormones and Behavior 120, 104685, 2020. https://doi.org/10.1016/j.yhbeh.2020.104685
    13. Arai, A., Hirota, Y., *Mitsui, S., Pair bond formation by monogamous prairie voles in novel environments. Kitakanto Medical Journal 69, 129-133, 2019. https://doi.org/10.2974/kmj.69.129
    14. Hidaka, C., Kashio, T., Uchigaki, D., *Mitsui, S., Vulnerability or resilience of motopsin knockout mice to maternal separation stress depending on adulthood behaviors. Neuropsychiatric Diseases and Treatment 14, 2255¬–2268, 2018. https://doi.org/10.2147/NDT.S170281
    15. Tsuchiya, K., Mitsui, S., Fukuyama, R., Yamaya, N., Fujita, T., Shimoda, K., *Tozato, F., An acute bout of housework activities has beneficial effecs on executive function. Neuropsychiatric Diseases and Treatment 14, 61–72, 2018. https://doi.org/10.2147/NDT.S153813
    16. *Osako, Y., Nobuhara, R., Arai, Y. P., Young, L. J., Nishihara, M., Mitsui, S., Yuri, K., Partner loss in monogamous rodents: Modulation of pain and emotional behavior in male prairie voles. Psychosomatic Medicine 80, 62–68, 2018. https://doi.org/10.1097/PSY.0000000000000524
    17. Arai, A., Hirota, Y., Miyase, N., Miyata, S., Young, L. J., Osako, Y., Yuri, K., *Mitsui, S., A single prolonged stress paradigm produces enduring impairments in social bonding in monogamous prairie voles. Behavioural Brain Research 315, 83–93, 2016. http://dx.doi.org/10.1016/j.bbr.2016.08.022
    18. Hidaka, C, *Mitsui, S., N-glycosylation modulates filopodia-like protrusions induced by sez-6 through regulating the distribution of this protein on the cell surface. Biochemical and Biophysical Research Communications 462, 346–351, 2015. doi: 10.1016/j.bbrc.2015.04.139
    19. Nakamura, K., Takabe, A., Shimizu, F., Takahashi, M., Matsuo, O., *Mitsui, S., Tissue plasminogen activator modulates emotion in a social context. Behavioural Brain Research 281, 24–31, 2015. doi: http://dx.doi.org/10.1016/j.bbr.2014.11.022
    20. *Mistui, S., Osako, Y., Yuri, K., The mental retardation-related protease, motopsin (prss12), binds to the BRICHOS domain of the integral membrane protein 2a. Cell Biology International 38, 117–¬123, 2014. doi: 10.1002/cbin.10164
    21. *Mitsui, S., Hidaka, C., Furihata, M., Osako, Y., Yuri, K., A mental retardation gene, motopsin/prss12, modulates cell morphology by interaction with seizure-related gene-6. Biochemical Biophysical Research Communications 436, 638–644, 2013. http://dx.doi.org/10.1016/j.bbrc.2013.04.112
    22. Higashi, K., Hasegawa, M., Yokoyama, C., Tachibana, T., Mitsui, S., Saito, K., Dermokine- impairs ERK signaling through direct binding to GRP78. FEBS Letters 586, 2300-2305, 2012. http://dx.doi.org/10.1016/j.febslet.2012.06.022
    23. Osaki, G., Mitsui, S., Yuri, K., The distribution of the seizure-related gene 6 (Sez-6) protein during postnatal development of the mouse forebrain suggests multiple functions for this protein: An analysis using a new antibody. Brain Research 1386, 58-69, 2011.
    24. *Mitsui, S., Osako, Y., Yokoi, Y., Dang, M. T., Yuri, K., Li Y., Yamaguchi, N., A mental retardation gene, motopsin/neurotrypsin/prss12, modulates hippocampal function and social interaction. European Journal of Neuroscience 30, 2368-2378, 2009. https://doi.org/10.1111/j.1460-9568.2009.07029.x
    25. Mitsui, S., Watanabe, Y, Yamaguchi, T., Yamaguchi, N., Mosaic serine proteases in the mammalian central nervous system. Frontier in Biosciences 13, 1991-2000, 2008.
    26. Yokoi, F., Dang, T. Mai, Mitsui, S., Li, J., Li, Y., Motor deficits and hyperactivity in cerebral cortex-specific Dyt1 conditional knockout mice. Journal of Biochemistry, 143, 39-47, 2008.
    27. Mitsui, S.*, Yamaguchi, N., Osako, Y., Yuri, K., Enzymatic properties and localization of motopsin (PRSS12), a protease whose absence causes mental retardation. Brain Research 1136, 1-12, 2007.
    28. Mitsui, S., Nakamura, T., Okui, A., Kominami, K., Uemura, H., Yamaguchi, N., Multiple promoters regulate tissue-specific alternative splicing of the human kallikrein gene, KLK11/hippostasin. FEBS Journal 273, 3678-3686, 2006
    29. Numajiri, T., Mitsui, S., Hisa, Y., Ishida, T., Nishino, K., Yamaguchi, N., The expression of a motoneuron-specific serine protease, motopsin (PRSS12), after facial nerve　axotomy in mice. Journal of Plastic, Reconstructive & Aesthetic Surgery 59, 393-397, 2006
    30. Mitsui, S., Okui, A., Kominami, K., Konishi, E., Uemura, H., and Yamaguchi, N., A novel serine protease highly expressed in the pancreas is expressed in various kinds of cancer cells. FEBS Journal 272, 4911-4923, 2005
    31. Yokoi, F., Dang, M. T., Mitsui, S., and Li, Y., Exclusive paternal expression and novel alternatively spliced variants of -sarcoglycan mRNA in mouse brain. FEBS Letters 579, 4822-4828, 2005
    32. Watanabe, Y., Okui, A., Mitsui, S., Kawarabuki, K., Yamaguch, T., Uemura, H., and Yamaguchi N., Molecular cloning and tissue-specific expression analysis of mouse spinesin, a type II transmembrane serine protease 5. Biochemical Biophysical Research Communications 324, 333-340, 2004
    33. Higashi, K., Inagaki, Y., Suzuki, N., Mitsui, S., Mauviel, A., Kaneko, H., Nakatsuka, I., Y-box-binding Protein YB-1 Mediates Transcriptional Repression of Human α2(I) Collagen Gene Expression by Interferon-γ Journal of Biological Chemistry 278, 5156-5162, 2003.
    34. Nakamura T, Mitsui, S., Okui A, Miki T, Yamaguchi N: Molecular Cloning and Expression of a Variant Form of Hippostasin/KLK11in Prostate. The Prostate 54, 299-305, 2003.
    35. Mitsui, S., Okui A, Uemura H, Mizuno T, Yamada T, Yamamura T, Yamaguchi N: Decreased cerebrospinal fluid levels of neurosin (KLK6), an ageing-related protease, as a possible new risk factor for Alzheimer’s disease. Annals of NewYork Academy of Science 977: 216-223, 2002.
    36. Sogame Y, Kataoka K, Kato M, Sakagami J, Osawa S, Takatera A, Mitsuyoshi M, Usui N, Mitsui, S., Yamaguchi N: Molecular cloning and characterization of chymopasin, a novel serine protease from rat pancreas. Pancreas 25: 378-386, 2002.
    37. Yamaguchi N, Okui A, Yamada T, Nakazato H, Mitsui, S., Spinesin/TMPRSS5, a novel transmembrane serine protease, cloned from human spinal cord. Journal of Biological Chemistry 277, 6806-6812, 2002.
    38. Diamandis E P, Okui A, Mitsui, S., Luo L Y, Soosaipillai A, Grass L, Nakamura T, Howarth D J, Yamaguchi N., Human kallikrein 11: a new biomarker of prostate and ovarian carcinoma. Cancer Research 62, 295-300, 2002.
    39. Nakamura T, Mitsui, S., Okui A, Kominami K, Nomoto T, Ukimura O, Kawauchi A, Miki T, Yamaguchi N., Alternative splicing isoforms of hippostasin (PRSS20/KLK11) in prostate cancer cell lines. The Prostate 49, 72-78, 2001.
    40. Okui A, Kominami K, Uemura H, Mitsui, S., Yamaguchi N., Characterization of a brain-related serine protease, neurosin (human kallikrein 6) in human cerebrospinal fluid. NeuroReport 12, 1345-1350, 2001.
    41. Mitsui, S., Ohuchi A, Adachi-Yamada T, Hotta M, Tsuboi R, Ogawa H: Cyclin-dependent kinase inhibitors, p21waf1/cip1 and p27kip1, are expressed site- and hair cycle-dependently in rat hair follicles. Journal of Dermatological Science 25, 164-169, 2001.
    42. Lee, Y.-R., Yamazaki, M., Mitsui, S., Tsuboi, R., and Ogawa, H: Hepatocyte growth factor (HGF) activator expressed in hair follicles is involved in in vitro HGF-dependent hair follicle elongation. Journal of Dermatological Science 25, 165-163, 2001.
    43. Mitsui, S., Oku, A, Kominami K, Uemura H, Yamaguchi N: cDNA cloning and tissue-specific splicing variants of mouse hippostasin/TLSP (PRSS20). Biochimica at Biophysica Acta 1494, 206-210, 2000.
    44. Mitsui, S., Yamada T, Okui A, Kominami K, Uemura H, Yamaguchi N., A novel isoform of a kallikrein-like protease, TLSP/Hippostasin (PRSS20), is expressed in the human brain and prostate. Biochemical Biophysical Research Communications 272, 205-211, 2000.
    45. Ogawa K, Yamada T, Tsujioka Y, Taguchi J, Takahashi M, Tsuboi Y, Fujino Y, Nakajima M, Yamamoto T, Akatsu H, Mitsui, S., Yamaguchi N., Localization of a novel type trypsin-like serine protease, neurosin, in brain tissues of Alzheimer's and Parkinson's disease. Psychiatry and Clinical Neuroscience 54, 419-426, 2000.
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